Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1979-2-12
pubmed:abstractText
Male and female Sprague-Dawley rats were exposed to freshly generated polyurethane foam dusts, in concentrations averaging 8.65 mg/m3 air, for 6 hours daily 5 days a week over a period of 12 weeks. For comparison the same numbers of rats were exposed to titanium dioxide (TiO2) (15.95 mg/m3 air), which is a known inert dust, and to air alone, as controls for the same exposure period. This exposure caused no noticeable changes in appearance, behavior, or body weight. The average lifespan values were within the normal range. A high tumor rate was seen in all groups, with no significant differences among the groups. No indications of a carcinogenic effect of the inhaled dusts on the respiratory tract could be established. The numerous tumors found in the different organs and groups were of a spontaneous nature. The observed lung-reactions are discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0146-4779
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
501-8
pubmed:dateRevised
2006-4-19
pubmed:meshHeading
pubmed:articleTitle
Inhalation studies with polyurethane foam dust in relation to respiratory tract carcinogenesis.
pubmed:publicationType
Journal Article