Linked Life Data

7222005

Source:http://linkedlifedata.com/resource/pubmed/id/7222005

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1981-6-13
pubmed:abstractText
The use of anabolic agents may give rise to residues in foods of animal origin and thus to potential effects on public health. Therefore, the physiology, metabolism and toxicity of the three endogenous hormones. 17 beta-oestradiol, progesterone and testosterone are discussed. In addition, the effects of the use of three exogenous hormones, diethylstilboestrol (DES), trenbolone and zeranol are evaluated. As can be expected all six compounds have effects on the endocrine system and reproduction. Endogenous hormones and DES are teratogenic at high-dose levels. With the exception of DES, there is no evidence of a mutagenic action. 17 beta-Oestradiol and testosterone were shown to induce tumours at high-dose levels in experimental animals; probably however, a threshold can be established. The residues in edible tissue resulting from the use of endogenous hormones are much smaller than are the natural levels in cow's milk and butter. In view of the carcinogenicity of DES in man, its use should be strongly discouraged. A definite statement on the acceptability of the use of trenbolone and zeranol cannot be made.
pubmed:language
dut
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0040-7453
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
106
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
353-66
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
[Toxicological aspects of the use of hormones as anabolic agents (author's transl)].
pubmed:publicationType
Journal Article, English Abstract