Linked Life Data

7221892

Source:http://linkedlifedata.com/resource/pubmed/id/7221892

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1981-6-23
pubmed:abstractText
The objective of this study was to determine the relationship of an intact nervous system to the lung in the development of pulmonary edema. After unilateral denervation of a lung by autotransplantation, eight dogs were subjected to a period of increased intracranial pressure with air. A significant increase in pulmonary artery pressure and a 20% right-to-left shunt developed in all animals. The innervated lung of the animals subjected to increased intracranial pressure developed higher wet/dry lung weight ratios and 51Cr platelet counts compared to denervated lungs and to the five control innervated lungs. Thus intrapulmonary platelet sequestration and pulmonary edema occurred only in the intact innervated lung. These findings support the thesis that pulmonary edema following elevation of the intracranial pressure with air is the result of neurally induced alterations in pulmonary hemodynamics and platelet sequestration that could possibly lead to an increase in pulmonary vascular permeability.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0039-6060
pubmed:author
pubmed:issnType
Print
pubmed:volume
89
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
617-21
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Effect of lung denervation on development of pulmonary edema.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.