Linked Life Data

7218257

Source:http://linkedlifedata.com/resource/pubmed/id/7218257

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1981-6-25
pubmed:abstractText
We previously reported that the chemotactic response of granulocytes from the patients with Behcet's disease is higher than normal neutrophils. In this study we examined the mechanism by which neutrophils from the patients with Behcet's disease were hyperchemotactic. Normal and patients' leukocytes were disrupted in hypertonic sucrose, sonicated and the supernate was examined. The extracts from the disrupted Behcet's neutrophils increased the normal granulocyte response to the chemotactic stimulus more strongly than extracts from normal cells. This active substance was localized mainly in the cytoplasmic fraction of leukocytes. The fact that Behcet's neutrophils have a higher concentration of the cytoplasmic activator might play an important role in the pathogenesis of hyperchemotaxis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0315-162X
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
40-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
The mechanism of hyperchemotaxis in Behçet's disease.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't