Linked Life Data

7218005

Source:http://linkedlifedata.com/resource/pubmed/id/7218005

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1981-6-23
pubmed:abstractText
A morphologic (light-, electron microscopic, and immunohistochemical) study of a spontaneous ovarian teratoma, originating in the LT strain of mice and showing predominantly neural differentiation, has revealed an unusually large number of mature myelinated axons and synapses within areas of well-differentiated neuroepithelium. Most of the myelin was determined to be of CNS origin by its staining characteristics with the LFB-PAS stain, the absence of reticulin fibers by light microscopy and of basal laminae by electron microscopy in relation to the myelin sheaths, the presence of associated cells identified morphologically as oligodendrocytes, and by the strongly positive immunohistologic reaction obtained for myelin basic protein. Most synapses likewise appeared to be of the CNS type. This murine ovarian teratoma may therefore be a useful tool for the study of neoplastic myelinogenesis and synaptogenesis.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0022-3069
pubmed:author
pubmed:issnType
Print
pubmed:volume
40
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
289-97
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
CNS myelin and synapses in a spontaneous mouse ovarian teratoma showing neural differentiation. An immunohistochemical and electron microscopic study.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.