Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1981-6-23
|
pubmed:abstractText |
An antigenic fraction of Salmonella typhi strain TY6S, obtained from a bacterial pellet by washings with 1.5 M NaCl and ultracentrifugation in a 5%-20% sucrose density gradient, induced serum antibodies in rabbits that protected chicken embryos challenged with lethal doses of the virulent microorganism. The antigenic preparation was free of Vi, O, and H antigens. It contained about 85% protein and Rd1P+ lipopolysaccharide. The protein moiety comprised three polypeptides of 45,000, 32,000, and 20,000 daltons, respectively. In addition, the purified preparation exhibited the properties of a bacterial adhesin with receptor-like activity for mannosyl residues, as shown by agglutination of target cells containing these residues at their surfaces.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
0022-1899
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
143
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
106-13
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:7217708-Animals,
pubmed-meshheading:7217708-Antibodies, Bacterial,
pubmed-meshheading:7217708-Antigens, Bacterial,
pubmed-meshheading:7217708-Centrifugation, Density Gradient,
pubmed-meshheading:7217708-Chick Embryo,
pubmed-meshheading:7217708-Humans,
pubmed-meshheading:7217708-Immunization,
pubmed-meshheading:7217708-Mannose,
pubmed-meshheading:7217708-Rabbits,
pubmed-meshheading:7217708-Receptors, Antigen,
pubmed-meshheading:7217708-Salmonella typhi,
pubmed-meshheading:7217708-Species Specificity
|
pubmed:year |
1981
|
pubmed:articleTitle |
Isolation of an (O,H,Vi)-free immunoprotective antigenic fraction with mannose receptor-like activity from Salmonella typhi.
|
pubmed:publicationType |
Journal Article
|