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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1981-6-13
|
| pubmed:abstractText |
With carmine particles used as markers, no significant difference was observed between the phagocytic activity of 1- to 3-week-old confluent monolayer cultures of normal and dystrophic retinal pigment epithelial (RPE) cells harvested from 1-day-old Royal College of Surgeons rats. The phagocytic activity of both normal and dystrophic RPE was markedly suppressed in a medium containing 1 mg/ml arachidonic acid (AA), and the cells rapidly assumed a rounded profile. With 100 micrograms/ml AA, the phagocytic activity of dystrophic RPE was differentially reduced compared with that of the normal sample (p greater than or equal to 0.001); this effect was subsequently accompanied by a gradual change in the shape of the cells. Lower concentrations of AA (5 microgram/ml and below) did not produce a significant effect in either group.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0146-0404
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
20
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
553-7
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading | |
| pubmed:year |
1981
|
| pubmed:articleTitle |
Effect of arachidonic acid on normal and dystrophic retinal pigment epithelium in tissue culture.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|