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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1981-5-21
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pubmed:abstractText |
The effect of different dosage regimens of aspirin was investigated in an experimental model of arterial thrombosis. A paradoxical effect with an increase of the arterial thrombus growth could be seen after a first single dose of 100 mg aspirin/kg body weight. When the high dose of aspirin was given repeatedly, a thrombus size minor than under low dose aspirin therapy with 10 mg/kg body weight has been observed. Our experimental thrombosis experiments do not provide sufficient evidence to support antithrombotic therapy with low doses of aspirin.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0098-6127
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
8
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
422-5
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:7213048-Animals,
pubmed-meshheading:7213048-Aorta, Abdominal,
pubmed-meshheading:7213048-Arteries,
pubmed-meshheading:7213048-Aspirin,
pubmed-meshheading:7213048-Blood Coagulation,
pubmed-meshheading:7213048-Body Weight,
pubmed-meshheading:7213048-Dose-Response Relationship, Drug,
pubmed-meshheading:7213048-Rabbits,
pubmed-meshheading:7213048-Thrombosis
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pubmed:year |
1980
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pubmed:articleTitle |
Paradoxical effect of high and low dose aspirin in experimental arterial thrombosis.
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pubmed:publicationType |
Journal Article
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