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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1981-5-21
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pubmed:abstractText |
Human seminal plasma, (HuSePl) is inhibitory to mitogen (PHA-M, Con-A, and PWM) lymphocyte activation. The inhibition does not require the continuous presence of HuSePl. Lymphocyte cultures remain inhibited after 24-hr contact with HuSePl and subsequent washings. Addition of fresh autochthonous lymphocytes or T cells but not B cells can restore the mitogenic activity of HuSePl-inhibited lymphocyte cultures. These observations suggest that T-lymphocyte in the male genital tract are surveilled by HuSePl and lack of inhibitory material could induce an immunologic response by spermatozoal antigens.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
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pubmed:issn |
0148-5016
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
67-74
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7212851-Cells, Cultured,
pubmed-meshheading:7212851-Concanavalin A,
pubmed-meshheading:7212851-Humans,
pubmed-meshheading:7212851-Immunity, Cellular,
pubmed-meshheading:7212851-Lymphocytes,
pubmed-meshheading:7212851-Male,
pubmed-meshheading:7212851-Mitosis,
pubmed-meshheading:7212851-Pokeweed Mitogens,
pubmed-meshheading:7212851-Semen
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pubmed:year |
1981
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pubmed:articleTitle |
In vitro studies in reproductive immunology. 3. Restoration of mitogenic activity of lymphocytes inhibited by seminal plasma in man.
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pubmed:publicationType |
Journal Article
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