Linked Life Data

720449

Source:http://linkedlifedata.com/resource/pubmed/id/720449

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-6
pubmed:dateCreated
1979-2-12
pubmed:abstractText
The activity of hexobarbital metabolising enzymes of the liver is decreased as a consequence of both acute and chronical carbon tetrachloride damage. Simultaneous administration of estrogens was followed by more severe morphological and functional impairment although estrogens are not burdening the healthy liver. The beta receptor blocking propranolol prevented functional lesion, moderated fatty degeneration and liver cell necrosis in chronic carbon tetrachloride injury. A simultaneous estrogen administration decreased the therapeutic efficacy of beta blockade, however functional and morphological protective effects were not completely abolished. Estrogen medication should be rather avoided in hepatic damage.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0014-4908
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
283-90
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1978
pubmed:articleTitle
Estrogens as disposing factors in experimental liver injury.
pubmed:publicationType
Journal Article