Linked Life Data

7202098

Source:http://linkedlifedata.com/resource/pubmed/id/7202098

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1982-10-12
pubmed:abstractText
Autoxidation of pure soybean phosphatidylcholine liposomes at 40 C was found to proceed without an observed induction period, but otherwise, the rates of disappearance of the linoleic acid (70% of total) and linolenic acid (6% of total) followed typical autocatalytic kinetics. Incorporation of 0.05 mol % of tocopherol into the liposomes produced an induction period of about 7 hr under the condition used for the incubation. The products formed from the autoxidation of pure soybean phosphatidylcholine liposomes were mostly 9- and 13-hydroperoxyoctadecadienoates (isolated as hydroxy esters). The yield of hydroperoxides with cis,trans configuration was about the same as those with trans,trans configuration throughout incubation period. After extensive autoxidation, a large quantity of trihydroxyoctadecenoate was also produced. When a large quantity of dipalmitoyl phosphatidylcholine was incorporated into soybean phosphatidylcholine liposomes, the rate of autoxidation decreased and was found to conform to apparent first-order kinetics. In this system, the yield of trans,trans hydroperoxides was much greater than that of cis,trans isomers at all stages of autoxidation. Late in the autoxidation of the mixed liposomes, both trihydroxyoctadecenoate and hydroxyepoxyoctadecenoate were produced in substantial quantities.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0024-4201
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
403-13
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Autoxidation of phosphatidylcholine liposomes.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't