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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
|
pubmed:dateCreated |
1982-8-26
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pubmed:abstractText |
Human urine concentrates, prepared with the use of XAD-2 resin, are shown to be potent inducers of sister-chromatid exchanges, and especially of chromosomal damage and cell-cycle delay in Chinese hamster ovary cells. No indications for differences in mutagenic activity were found between concentrates prepared from the urine of smokers, non-smokers or patients with alcoholic cirrhosis of the liver. These effects were obtained without metabolic activation in vitro. Experiments including variations in preparative procedures indicate that a quick saturation of the resin by non-polar compounds from human urine may lead to an underestimation of the amount of mutagenic substances in a given urine sample.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0027-5107
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
22
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pubmed:volume |
92
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
333-60
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:7201069-Animals,
pubmed-meshheading:7201069-Cell Cycle,
pubmed-meshheading:7201069-Cell Line,
pubmed-meshheading:7201069-Chromosome Aberrations,
pubmed-meshheading:7201069-Chromosomes,
pubmed-meshheading:7201069-Cricetinae,
pubmed-meshheading:7201069-Cricetulus,
pubmed-meshheading:7201069-Crossing Over, Genetic,
pubmed-meshheading:7201069-Female,
pubmed-meshheading:7201069-Humans,
pubmed-meshheading:7201069-Mutagens,
pubmed-meshheading:7201069-Ovary,
pubmed-meshheading:7201069-Sister Chromatid Exchange,
pubmed-meshheading:7201069-Urine
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pubmed:year |
1982
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pubmed:articleTitle |
Induction of sister-chromatid exchanges, cell-cycle delay and chromosomal aberrations by human urine concentrates.
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pubmed:publicationType |
Journal Article
|