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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1982-5-12
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pubmed:abstractText |
51Cr-platelet kinetics study was performed in 197 patients with chronic ITP after corticosteroid therapy had failed to induce a long lasting remission. The incidence of splenic, spleno-hepatic, hepatic and diffuse platelet sequestration site was 58%, 17%, 6% and 19%, respectively. Splenic and spleno-hepatic sequestration sites were more frequent in patients less than 30 years old and in patients with a platelet count lower than 50 x 10(9)/1. 111 patients were splenectomized shortly after the study. Normalization of the platelet count was obtained more frequently in patients with splenic and spleno-hepatic sequestration than in the others. Labelled platelet sequestration site was the best predictor of the outcome of splenectomy. Platelet kinetics is a non-invasive investigation that should be performed early after the diagnosis of chronic ITP in all patients eligible for splenectomy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
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pubmed:issn |
0036-553X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
26
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
407-12
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7199755-Adolescent,
pubmed-meshheading:7199755-Adult,
pubmed-meshheading:7199755-Aged,
pubmed-meshheading:7199755-Blood Platelets,
pubmed-meshheading:7199755-Child,
pubmed-meshheading:7199755-Child, Preschool,
pubmed-meshheading:7199755-Chromium Radioisotopes,
pubmed-meshheading:7199755-Chronic Disease,
pubmed-meshheading:7199755-Female,
pubmed-meshheading:7199755-Humans,
pubmed-meshheading:7199755-Infant,
pubmed-meshheading:7199755-Kinetics,
pubmed-meshheading:7199755-Male,
pubmed-meshheading:7199755-Middle Aged,
pubmed-meshheading:7199755-Platelet Count,
pubmed-meshheading:7199755-Purpura, Thrombocytopenic,
pubmed-meshheading:7199755-Splenectomy
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pubmed:year |
1981
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pubmed:articleTitle |
Chronic idiopathic thrombocytopenic purpura (ITP): site of platelet sequestration and results of splenectomy. A study of 197 patients.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|