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rdf:type |
|
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lifeskim:mentions |
|
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pubmed:issue |
6
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|
pubmed:dateCreated |
1981-11-18
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|
pubmed:abstractText |
The effects of sodium hydroxybutyrate (100 mg/kg); phenazepam (1 mg/kg), apomorphine (0.1 mg/kg and haloperidol (1 mg/kg) on the electrophysiological sleep pattern were studied in rats during 7-day alcohol withdrawal after its voluntary consumption for 13 months. It was shown that alcohol withdrawal led to profound disorders in the sleep-waking cycle. Sodium hydroxybutyrate prevented these disturbances and brought sleep to normal. Phenazepam exerted a powerful sedative and hypnotic effects but did not improve the balance of sleep phases. Apomorphine displayed a tendency to sleep normalization. However, this effect was short-term. Haloperidol did not eliminate abstinence manifestations in the sleep pattern.
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pubmed:language |
rus
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Jun
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|
pubmed:issn |
0365-9615
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
91
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
689-91
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:7196780-Alcoholism,
pubmed-meshheading:7196780-Animals,
pubmed-meshheading:7196780-Anti-Anxiety Agents,
pubmed-meshheading:7196780-Apomorphine,
pubmed-meshheading:7196780-Benzodiazepines,
pubmed-meshheading:7196780-Benzodiazepinones,
pubmed-meshheading:7196780-Haloperidol,
pubmed-meshheading:7196780-Humans,
pubmed-meshheading:7196780-Male,
pubmed-meshheading:7196780-Psychotropic Drugs,
pubmed-meshheading:7196780-Rats,
pubmed-meshheading:7196780-Sleep Disorders,
pubmed-meshheading:7196780-Sodium Oxybate,
pubmed-meshheading:7196780-Substance Withdrawal Syndrome
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|
pubmed:year |
1981
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|
pubmed:articleTitle |
[Effect of psychotropic drugs on sleep disorders in rats during alcohol withdrawal].
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|
pubmed:publicationType |
Journal Article,
English Abstract
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