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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1981-10-14
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pubmed:abstractText |
It has been shown in experiments on rats that a single administration of phenazepam in doses of 0.5 and 2 mg/kg reduces the period of falling asleep and of being conscious, shortens the duration of the paradoxical sleep phase and increases the duration of slow-wave sleep thereby indicating the intensity of the drug hypnotic effect. Prolonged (10 days) administration of phenazepam does not induce tolerance. However, after the drug discontinuation there develops a withdrawal syndrome that is characterised by changes in the sleep structure.
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pubmed:language |
rus
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0014-8318
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
18-20
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:7196341-Animals,
pubmed-meshheading:7196341-Anti-Anxiety Agents,
pubmed-meshheading:7196341-Benzodiazepines,
pubmed-meshheading:7196341-Benzodiazepinones,
pubmed-meshheading:7196341-Drug Tolerance,
pubmed-meshheading:7196341-Humans,
pubmed-meshheading:7196341-Male,
pubmed-meshheading:7196341-Rats,
pubmed-meshheading:7196341-Sleep,
pubmed-meshheading:7196341-Sleep Disorders,
pubmed-meshheading:7196341-Sleep Stages,
pubmed-meshheading:7196341-Substance Withdrawal Syndrome
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pubmed:articleTitle |
[Effect of phenazepam on sleep cycles in rats].
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pubmed:publicationType |
Journal Article,
English Abstract
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