Linked Life Data

719630

Source:http://linkedlifedata.com/resource/pubmed/id/719630

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1979-2-12
pubmed:abstractText
It has been postulated that the intestinal anaerobes play a role in the etiology of large bowel cancer. This study was designed to characterize and compare the fecal anaerobes of patients with large bowel cancer, patients with nonhereditary large bowel polyps, and healthy control subjects. Although some distributional variations of the anaerobic genera were observed among the study groups, significant differences in fecal anaerobic microflora and total aerobic counts were not noted. This suggests that taxonomic grouping of fecal bacteria is an inadequate measure of relative risk of developing large bowel cancer. However, the fecal microbial 7alpha-dehydroxylase and cholesterol dehydrogenase activities of large bowel cancer patients and patients with nonhereditary large bowel polyps were significantly higher than those of healthy control subjects. On the other hand, no significant difference in fecal microbial beta-glucuronidase activity was noted among the study groups. It may be that assessment of the total metabolic activities of the intestinal microflora will provide a better understanding of their potential role in the genesis of large bowel cancer.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0008-5472
pubmed:author
pubmed:issnType
Print
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
4458-62
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1978
pubmed:articleTitle
Fecal profiles of anaerobic microflora of large bowel cancer patients and patients with nonhereditary large bowel polyps.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S.