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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
|
pubmed:dateCreated |
1981-3-24
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pubmed:abstractText |
Antireceptor antibodies anti- (CBA-anti-C57BL/6) and anti-(C57BL/6-anti-BALB/c) were obtained in a heterologous system by immunization of rabbits with alloimmune mouse lymphocytes and intensive absorption of immune rabbit sera. In the complement-dependent cytotoxic assay, these antireceptor antibodies were able to lyse only T-lymphoblasts with corresponding idiotypic specificity but not T-lymphoblasts of other idiotypes and normal T- and B- lymphocytes of various strains. It was also shown that antireceptor antibodies specifically inhibit the lethal graft-versus-host disease after injection of allogenic parental spleen cells into irradiated F1-recipients. These results suggest that heterologous antireceptor antibodies are capable of inhibiting specifically the immune responses to allogenic transplantation antigens.
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pubmed:language |
rus
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0365-9615
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
90
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
588-90
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pubmed:dateRevised |
2008-10-8
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pubmed:meshHeading |
pubmed-meshheading:7192584-Animals,
pubmed-meshheading:7192584-Antilymphocyte Serum,
pubmed-meshheading:7192584-Cytotoxicity Tests, Immunologic,
pubmed-meshheading:7192584-Female,
pubmed-meshheading:7192584-Graft vs Host Disease,
pubmed-meshheading:7192584-Male,
pubmed-meshheading:7192584-Mice,
pubmed-meshheading:7192584-Mice, Inbred BALB C,
pubmed-meshheading:7192584-Mice, Inbred C57BL,
pubmed-meshheading:7192584-Mice, Inbred CBA,
pubmed-meshheading:7192584-Rabbits,
pubmed-meshheading:7192584-Receptors, Antigen, T-Cell
|
pubmed:year |
1980
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pubmed:articleTitle |
[Use of heterologous antireceptor antibodies for specific reversal of acute homologous disease in mice].
|
pubmed:publicationType |
Journal Article,
English Abstract
|