Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1980-11-25
pubmed:abstractText
The effect of a pretreatment dose (0.014 mg/kg) of pancuronium bromide on pulmonary function tests in 15 healthy volunteers was investigated. Ventilatory flow volume loops and maximum voluntary ventilation were determined before and 1 and 3 minutes following administration of the pancuronium. Calculation of the pulmonary function from the flow volume loops revealed statistically significant decreases in forced expiratory flow at 50% of expired volume, forced expiratory volume at 1 second and 3 seconds, peak inspiratory flow, peak inspiratory flow at 50% of inspired volume, forced vital capacity, and maximum voluntary ventilation. Significant pulmonary dysfunction associated with dyspnea was seen in four subjects and one subject had to be artificially ventilated and pancuronium had to be reversed with prostigmine. Ventilation should be closely monitored in patients following pretreatment doses of pancuronium in view of frequent atypical responses.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0003-2999
pubmed:author
pubmed:issnType
Print
pubmed:volume
59
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
659-61
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Pulmonary function following 'pretreatment' dose of pancuronium in volunteers.
pubmed:publicationType
Journal Article