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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1980-8-15
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pubmed:abstractText |
In 17 Wistar rats isovolumetric pressure-volume diagrams, the rate of pressure rise, and the resting tension curve were recorded prior to and during acute alcohol intoxication. Ethyl alcohol was infused intravenously; parameters were recorded at blood alcohol levels between 0.6% and 0.2%. The following results were obtained. 1. In agreement with other authors, even slight amounts of alcohol induced significant cardiodepression. 2. At high blood alcohol levels the isovolumetric pressure-volume relation is shifted to higher enddiastolic volumes and pressures. 3. The alcohol-induced cardiodepression is dose-dependent. There is a linear correlation between the maximum rate of pressure rise and the blood alcohol level.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0300-8428
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
75
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
279-80
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7190009-Alcoholic Intoxication,
pubmed-meshheading:7190009-Animals,
pubmed-meshheading:7190009-Blood Pressure,
pubmed-meshheading:7190009-Blood Volume,
pubmed-meshheading:7190009-Diastole,
pubmed-meshheading:7190009-Heart Ventricles,
pubmed-meshheading:7190009-Humans,
pubmed-meshheading:7190009-Male,
pubmed-meshheading:7190009-Myocardial Contraction,
pubmed-meshheading:7190009-Rats,
pubmed-meshheading:7190009-Systole
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pubmed:articleTitle |
Influence of acute alcohol intoxication on the left ventricular pressure-volume relations of the rat heart.
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pubmed:publicationType |
Journal Article
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