Linked Life Data

718798

Source:http://linkedlifedata.com/resource/pubmed/id/718798

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1979-2-21
pubmed:abstractText
Rats were fed diets containing 0.5 mg or 50 mg of chrysotile asbestos each day for 1 week or 14 months and tissues of the gastrointestinal tract were examined by light and electron microscopy. At the light microscope level the oesophagus, stomach and caecum in treated animals appeared unaffected, whereas accumulation of cellular debris and Alcian blue-positive material was apparent in the ileal, rectal and colonic lumens. Electron microscope examination of the colon and ileum of rats ingesting 50 mg chrysotile/day for 14 months confirmed these findings and indicated changes in the mucosal lining cells of the ileum which were consistent with a mineral-induced cytotoxicity. These results are compared with those reported in a similar previous biochemical study and the specificity of asbestos action on certain regions of the gastrointestinal tract is discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0007-1021
pubmed:author
pubmed:issnType
Print
pubmed:volume
59
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
443-53
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1978
pubmed:articleTitle
Light and electron microscope studies of the rat digestive tract following prolonged and short-term ingestion of chrysotile asbestos.
pubmed:publicationType
Journal Article