Linked Life Data

7186021

Source:http://linkedlifedata.com/resource/pubmed/id/7186021

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1983-10-8
pubmed:abstractText
[14C]Phenylalanine, either as free amino acid or as glycyl-phenylalanine, was continuously infused over 3 h into the portal or femoral vein of anaesthetized Wistar rats. Radioactive phenylalanine and metabolites, as well as labelled proteins, were determined in plasma during infusion and at the end of the experiments in kidney, liver, brain, heart, and femoral muscle. No differences in plasma and tissue pools were observed, if the results after portal versus femoral infusion are compared. The infusion of peptide-linked phenylalanine results in a distribution of radioactivity similar to that occurring after infusion of the free amino acid. Peptidase activity toward glycyl-phenylalanine was found in plasma as well as tissues. The unhydrolyzed dipeptide could not be detected in plasma or in the tissues. These data suggest that administration of nutrients into the peripheral vein does not alter their metabolic fate.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0277-2116
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
125-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Metabolic fate of free and peptide-linked phenylalanine during infusion into portal or femoral vein of rats.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't