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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1983-8-17
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pubmed:abstractText |
Effects of lysozyme(LY) alone and combination with various antitumor agents were examined using syngeneic tumors mainly Meth-A and MH 134 transplanted into Balb/c and C3H/He mice, respectively. The effects of LY on pulmonary metastases were also examined in BDF1 mice bearing Lewis lung carcinoma (3LL). LY inhibited the growth of Meth-A tumor and enhanced antitumor effects of mitomycin C (MMC). bleomycin (BLM) and 5-fluorouracil (5-FU), LY activated antitumor effects of MMC, BLM and 5-FU on MH 134 tumor, however, LY alone did not show any significant antitumor effect on it. The combination treatments using LY with MMC or 5-FU showed a marked inhibition on pulmonary metastases of 3LL. The pre-treatment of LY inhibited the tumor growth of Sarcoma-180 in ICR mice.
|
pubmed:language |
jpn
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
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pubmed:issn |
0385-0684
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
915-23
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7184434-Animals,
pubmed-meshheading:7184434-Antineoplastic Agents,
pubmed-meshheading:7184434-Drug Synergism,
pubmed-meshheading:7184434-Female,
pubmed-meshheading:7184434-Fluorouracil,
pubmed-meshheading:7184434-Mice,
pubmed-meshheading:7184434-Mitomycins,
pubmed-meshheading:7184434-Muramidase,
pubmed-meshheading:7184434-Neoplasms, Experimental
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pubmed:year |
1982
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pubmed:articleTitle |
[Experimental studies on antitumor effects of lysozyme].
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pubmed:publicationType |
Journal Article,
English Abstract
|