Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1983-2-14
pubmed:abstractText
2 patients with early-stage chronic lymphocytic leukaemia had involvement of the central nervous system causing dementia as the predominant clinical symptom. None of the patients had focal neurological abnormalities. One patient was successfully treated first with irradiation therapy to the central nervous system, and later with intrathecal administration of methotrexate. The other patient died with massive leukaemic infiltration of the central nervous system before effective treatment had been given. Although significant involvement of the central nervous system is rare in chronic lymphocytic leukaemia and usually does not occur until late in the disease, these cases show that clinically important infiltration may happen very early. The clinical picture of dementia has not been described in chronic lymphocytic leukaemia.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0036-553X
pubmed:author
pubmed:issnType
Print
pubmed:volume
29
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
283-6
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Dementia and central nervous system involvement in chronic lymphocytic leukaemia.
pubmed:publicationType
Journal Article