Linked Life Data

7175983

Source:http://linkedlifedata.com/resource/pubmed/id/7175983

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1983-2-25
pubmed:abstractText
The possible functional significance of the close relation between structural and metabolic steady-states of isolated rat liver mitochondria, has been investigated by analysing the metabolic consequences of a primary block of the structural modifications. The structural changes have been blocked by means of factors acting primarily on the structure and the block was evaluated by electron microscope and angular light scattering measurements. Evidence has been obtained that: (a) the phosphorylative capacity of isolated mitochondria is not modified by conditions that completely abolish the structural changes; therefore, the configurational changes do not constitute as such a mechano-chemical mechanism for energy conservation and transformation. (b) The block of the structural changes is closely associated with the impairment of respiratory control: in fact there appears to be a close relation between the capacity of mitochondria to vary their structure and the ability to vary the respiratory rate, both being a function of ADP concentration.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0022-4782
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
461-70
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
The relation between structural and metabolic steady-states in isolated rat liver mitochondria. A study of the functional significance.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't