Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3-4
|
pubmed:dateCreated |
1983-2-14
|
pubmed:abstractText |
[3H]-salbutamol added in tracer doses (approximately equal to 250 nmol per animal) to the carrier solution (20 mg/kg) was injected intraperitoneally to pregnant rats on the 19th day of gestation. Some experiments were performed with intravenous administration (approximately equal to 2.5 microCi in 300 microliters 9 g/l NaCl). Drug distribution was studied in the maternal and fetal plasma, lung and liver, and in the placenta and amniotic fluid. 10% of the maternal salbutamol plasma radioactivity was recovered in the fetal plasma, in accordance with earlier findings reported from our laboratory using human placental lobules in vitro.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0379-8305
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
4
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
151-7
|
pubmed:dateRevised |
2003-11-14
|
pubmed:meshHeading |
pubmed-meshheading:7172972-Albuterol,
pubmed-meshheading:7172972-Amniotic Fluid,
pubmed-meshheading:7172972-Animals,
pubmed-meshheading:7172972-Female,
pubmed-meshheading:7172972-Fetus,
pubmed-meshheading:7172972-Gestational Age,
pubmed-meshheading:7172972-Maternal-Fetal Exchange,
pubmed-meshheading:7172972-Pregnancy,
pubmed-meshheading:7172972-Rats,
pubmed-meshheading:7172972-Rats, Inbred Strains,
pubmed-meshheading:7172972-Tissue Distribution
|
pubmed:year |
1982
|
pubmed:articleTitle |
[3H]-Salbutamol placental transfer in pregnant rats on the 19th day of gestation.
|
pubmed:publicationType |
Journal Article
|