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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1983-3-17
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pubmed:abstractText |
Clofoctol inhibits in vivo cell wall synthesis of B. subtilis and gives rise to an accumulation of UDP-N-acetyl-muramyl pentapeptide. However, in vitro peptidoglycan synthesis using a particulate membrane preparation is not inhibited by clofoctol. These results suggest that clofoctol does not inhibit a specific enzyme of the cell wall synthesis, and that the inhibition of the cell wall synthesis might be a secondary effect due to a disturbance of the cytoplasmic membrane.
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pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Anti-Bacterial Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Cresols,
http://linkedlifedata.com/resource/pubmed/chemical/Peptidoglycan,
http://linkedlifedata.com/resource/pubmed/chemical/Vancomycin,
http://linkedlifedata.com/resource/pubmed/chemical/clofoctol
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pubmed:status |
MEDLINE
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pubmed:issn |
0021-793X
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
13
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
515-24
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading | |
pubmed:articleTitle |
Action of clofoctol on bacterial cell wall synthesis.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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