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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1979-1-15
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pubmed:abstractText |
A 61-year-old man with Trichosporon cutaneum (T. cutaneum) prosthetic valve endocarditis is reported. He had had an aortic valve replacement for rheumatic heart disease 3 years earlier. Onset of the valve infection was subacute. A systolic murmur was noted on admission. Subsequently, he developed conjunctival hemorrhages, hematuria and transient episodes of confusion, aphasia and cranial nerve palsies. Three of 17 blood cultures taken over 3 weeks were positive for T. cutaneum. He was given amphotericin B (AmB) and 5-fluorocytosine (5FC); T. cutaneum infection of prosthetic aortic valve was identified. The aortic valve was replaced. Postoperatively he developed refractory ventricular fibrillation and died. Striking synergy to AmB-5FC and AmB-rifampin combinations was demonstrated in vitro.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0036-5548
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
225-6
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:715385-Amphotericin B,
pubmed-meshheading:715385-Aortic Valve,
pubmed-meshheading:715385-Cryptococcosis,
pubmed-meshheading:715385-Cryptococcus,
pubmed-meshheading:715385-Endocarditis, Subacute Bacterial,
pubmed-meshheading:715385-Flucytosine,
pubmed-meshheading:715385-Heart Valve Prosthesis,
pubmed-meshheading:715385-Humans,
pubmed-meshheading:715385-Male,
pubmed-meshheading:715385-Middle Aged
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pubmed:year |
1978
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pubmed:articleTitle |
Trichosporon cutaneum endocarditis.
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pubmed:publicationType |
Journal Article,
Case Reports
|