rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
6
|
pubmed:dateCreated |
1983-3-17
|
pubmed:abstractText |
Thirty-two patients with epilepsy were typed for 26 HLA-A, -B and -C antigens. Sixteen of the patients were treated with phenytoin. They all had serum IgA concentrations below 0.20 g/l. Another 16 patients received carbamazepine. This group had showed a marked decrease of IgA and IgM serum concentrations during their first month of carbamazepine monotherapy. Among those who showed an IgA deficiency during phenytoin treatment, 14 had the antigen HLA-A2. The frequency of HLA-A2 was similar between controls and patients who had reduced immunoglobulin levels after 1 month of carbamazepine treatment.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0192-0561
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
4
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
517-20
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:7152760-Adult,
pubmed-meshheading:7152760-Anticonvulsants,
pubmed-meshheading:7152760-Carbamazepine,
pubmed-meshheading:7152760-Dysgammaglobulinemia,
pubmed-meshheading:7152760-Epilepsy,
pubmed-meshheading:7152760-Female,
pubmed-meshheading:7152760-HLA Antigens,
pubmed-meshheading:7152760-Humans,
pubmed-meshheading:7152760-IgA Deficiency,
pubmed-meshheading:7152760-Immunoglobulin M,
pubmed-meshheading:7152760-Male,
pubmed-meshheading:7152760-Phenytoin
|
pubmed:year |
1982
|
pubmed:articleTitle |
HLA antigens in epileptic patients with drug-induced immunodeficiency.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|