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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1983-1-7
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pubmed:abstractText |
Five cases of neurogenic pulmonary oedema (NPE) are described. The causes were mechanical trauma to the skull, subarachnoid haemorrhage and epileptic seizure. In every case a frank pulmonary oedema was diagnosed that resolved within a few days. Treatment of the underlying disease resulted in a favourable outcome. The literature has been reviewed. The basic mechanism seems to be an increased intracranial pressure (ICP) precipitating an increased central sympathetic nerve activity mediated via peripheral alpha- or beta-adrenergic discharge. NPE results from a predominant alpha-receptor stimulation with massive increase in pre- and afterload. The major therapeutic efforts should be directed towards the underlying cause and, in addition, mechanical ventilation with passive hyperventilation is vital. High positive end-expiratory pressure should not be used without strict monitoring of ICP.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
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pubmed:issn |
0001-6101
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
212
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
267-71
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7148522-Adult,
pubmed-meshheading:7148522-Brain Diseases,
pubmed-meshheading:7148522-Epilepsy,
pubmed-meshheading:7148522-Female,
pubmed-meshheading:7148522-Humans,
pubmed-meshheading:7148522-Intracranial Pressure,
pubmed-meshheading:7148522-Male,
pubmed-meshheading:7148522-Middle Aged,
pubmed-meshheading:7148522-Pulmonary Edema,
pubmed-meshheading:7148522-Skull,
pubmed-meshheading:7148522-Subarachnoid Hemorrhage
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pubmed:year |
1982
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pubmed:articleTitle |
Neurogenic pulmonary oedema. A review of the pathophysiology with clinical and therapeutic implications.
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pubmed:publicationType |
Journal Article,
Case Reports
|