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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
1983-1-27
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pubmed:abstractText |
After intravenous administration of Tc-99m DMPE the flow-dependent kinetics were studied in dogs during induced ischemia and during induced maximal reactive hyperemia. A control group was also studied. Mean time-activity curves obtained from the myocardial wall were compared within the same intervention group and also with other groups. During reactive hyperemia, there was a rapid and absolute increase in uptake followed by a rapid washout, whereas during ischemia there was a slow and decreased uptake followed by a slow washout. The magnitude of Tc-99m DMPE uptake during reactive hyperemia was slightly less than that of Tl-201, but the decreased uptake with ischemia was about equal for the two agents. Following maximal uptake in the myocardium the effective half-life of Tc-99m DMPE was one-third to one-fourth that of Tl-201. The similar kinetics of Tc-99m DMPE compared to Tl-201 suggests its usefulness in the evaluation of ischemic heart disease.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Organotechnetium Compounds,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphines,
http://linkedlifedata.com/resource/pubmed/chemical/Radioisotopes,
http://linkedlifedata.com/resource/pubmed/chemical/Technetium,
http://linkedlifedata.com/resource/pubmed/chemical/Thallium,
http://linkedlifedata.com/resource/pubmed/chemical/technetium Tc 99m...
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0161-5505
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1102-10
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:7143092-Animals,
pubmed-meshheading:7143092-Coronary Circulation,
pubmed-meshheading:7143092-Coronary Disease,
pubmed-meshheading:7143092-Dogs,
pubmed-meshheading:7143092-Hyperemia,
pubmed-meshheading:7143092-Kinetics,
pubmed-meshheading:7143092-Myocardium,
pubmed-meshheading:7143092-Organotechnetium Compounds,
pubmed-meshheading:7143092-Phosphines,
pubmed-meshheading:7143092-Radioisotopes,
pubmed-meshheading:7143092-Technetium,
pubmed-meshheading:7143092-Thallium
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pubmed:year |
1982
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pubmed:articleTitle |
Effect of coronary blood flow on uptake and washout of Tc-99m DMPE and Tl-201.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.
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