Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1983-1-19
pubmed:abstractText
Four glyceroglycolipids containing dipalmitylglycerol were synthesized. The thermotropic behavior and barrier function of aqueous suspensions of these glyceroglycolipids were studied. The gel to liquid crystalline phase transition temperatures of these glycolipids were higher than that of dipalmitoylphosphatidylcholine. The interaction between headgroups in glyceroglycolipids might be stronger than that in dipalmitoylphosphatidylcholine. Diglycosyl dipalmitylglycerols could form liposomes and function as a barrier against water-soluble small molecules (glucose, UmP, and H+) when assayed below their phase transition temperatures, like dipalmitoylphosphatidylcholine liposomes. The fundamental properties of glyceroglycolipid membranes so far examined were rather similar to those of phospholipid membranes, with the exception that the permeability rate of water through glycolipid membranes was higher than that through phospholipid membranes. This property might cause the apparent sensitivity difference between liposomes prepared from glycolipids and those from phospholipids to amphotericin B.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0021-924X
pubmed:author
pubmed:issnType
Print
pubmed:volume
92
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
953-60
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Physical properties and barrier functions of synthetic glyceroglycolipids.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't