Linked Life Data

7139237

Source:http://linkedlifedata.com/resource/pubmed/id/7139237

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
659
pubmed:dateCreated
1983-1-19
pubmed:abstractText
Patients with ankylosing spondylitis (AS) sometimes develop apical lung fibrosis and cavitation. It has been suggested that one causative factor is reduced apical ventilation due to rigidity of the thoracic cage. We measured regional ventilation in 27 patients with AS and 18 normal volunteers. Twelve patients (Group A) had chest expansion greater than 2 cm, twelve (Group B) had chest expansion of 2 cm or less and three (Group C) had apical lung lesions on chest radiographs; patients in Groups A and B had no radiographic lung lesions. Ventilation per unit volume (VE/VA min-1) was calculated from 81Krm washout curves. The ratio of upper zone to lower zone ventilation (VR) was calculated. VR in Group A (0.74 +/- 0.11) and group B (0.75 +/- 0.12) was not significantly different from VR in controls (0.76 +/- 0.08). There was no significant correlation between VR and FVC, FEV1 or maximal chest expansion. In patients with apical fibrosis only the radiographically abnormal areas had reduced ventilation. Patients with AS do not underventilate the upper zones of the lungs except in the presence of radiographically visible fibrosis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0007-1285
pubmed:author
pubmed:issnType
Print
pubmed:volume
55
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
833-6
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Regional lung ventilation in ankylosing spondylitis.
pubmed:publicationType
Journal Article