Linked Life Data

7138912

Source:http://linkedlifedata.com/resource/pubmed/id/7138912

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1983-1-19
pubmed:abstractText
Exposing HT-29 cells to the combination of two inducers of intestinal alkaline phosphatase, sodium butyrate and hyperosmolality, causes a synergistic (over 1000-fold) increase in specific activity. Evidence is presented showing that enzyme induction is reversible; the half-life of the induced activity is approximately 30 h. Preinduction by butyrate or by hyperosmolality does not prime the cells so as to respond synergistically when subsequently exposed to hyperosmolality or butyrate, respectively. This study demonstrates that when applied in combination, the effect on gene expression by one alkaline phosphatase inducer is amplified by the other.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0006-3002
pubmed:author
pubmed:issnType
Print
pubmed:day
8
pubmed:volume
718
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
220-3
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Synergistic induction of alkaline phosphatase in colonic carcinoma cells by sodium butyrate and hyperosmolality.
pubmed:publicationType
Journal Article