Linked Life Data

7138284

Source:http://linkedlifedata.com/resource/pubmed/id/7138284

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1982-12-18
pubmed:abstractText
12 patients suffering from sarcoidosis have been studied in addition to clinical and bioptic investigations, they were submitted to intradermal reaction with PPD, Candida Albicans and Kveim's antigen. Lymphocytes from the 12 patients were placed in culture and stimulated with phytohaemagglutinin (PHA), pokeweed mitogen (PWM), concanavalin A (CON-A), PPD, Candidin and Kveim's antigen. Six patients proved positive to Kveim's antigen in vivo, and four of them (66%) in vitro also. No patient was immunodepressed. Of the 6 patients negative to Kveim's antigen both in vivo and in vitro, 4 were clearly immunodepressed, as shown by the reduced mitogen response, the negative response to antigen stimulation, and to the intradermal reaction. The results are discussed in the light of recent findings regarding the role of the immunocompetent system in sarcoidosis.
pubmed:language
ita
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0004-0312
pubmed:author
pubmed:issnType
Print
pubmed:volume
139
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
183-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
[In vitro lymphocyte immunoreactivity in sarcoidosis patients. Stimulation with Kveim antigens].
pubmed:publicationType
Journal Article, Comparative Study, In Vitro, English Abstract