Linked Life Data

7137523

Source:http://linkedlifedata.com/resource/pubmed/id/7137523

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1982-12-16
pubmed:abstractText
The results of the skin, bronchial or conjunctival provocation tests and of the radioallergosorbent test (RAST) with dog dander and hair extract preparations from two different producers were compared. 202 asthmatic children were included in the study. The clinical tests, Al-RAST and paper RAST, were performed using only one allergen preparation (Hu073), while two allergen preparations (e2 and e5) were used in Phadebas RAST. A good correlation was generally found between the results of the clinical diagnostic tests, the clinical history and the results of RAST. Phadebas RAST e2 was the most specific but the least sensitive: it gave a class 0 result in 18% and class 3-4 in 34.5% of the subjects with a positive provocation test. The corresponding numbers for e5 RAST were 6.0% and 70.2%, respectively. Al-RAST was equally sensitive, but had lower specificity than Phadebas RAST e5. The correlation between Phadebas RAST e5 and paper RAST Hu 073 was excellent, which indicates a remarkable similarity between these allergen extracts. Using sensitive, immunochemically standardized Phadebas RAST e5 or Al-RAST methods, classes 0-1 can be regarded as negative, class 2 as doubtful and classes 3-4 as clinically positive results.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0105-4538
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
75-85
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
RAST in the diagnostic of dog dander allergy. A comparison between three allergen preparations using two variants of RAST.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't