Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1982-12-16
pubmed:abstractText
This study concerned 13 patients with diabetes mellitus who, although under insulin therapy treatment, had poor control of their diabetes. Motor conduction velocity (MCV) in the peroneal, ulnar and median nerves, sensory conduction velocity (SVC) of the median nerve and sensory potential amplitude (SPA) of the median nerve were determined immediately before and after 24 h of strict control of blood glucose by an artificial pancreas. A significant increase in the MCV of the ulnar nerve (P less than 0.01) and in the SCV of the median nerve (P less than 0.05) was found. This acute improvement led us to presume that repair of anatomic lesions would be extremely unlikely. Only a metabolic disturbance due to hyperglycemia can be rapidly corrected. This metabolite alteration may be held partly responsible for the slowing of nerve conduction in diabetes. No significant difference was noted in the MCV of the peroneal nerve and of the median nerve and the SPA of the median nerve. This suggests that advanced degenerative lesions are present in these nerves particularly in the lower limbs. Such lesions cannot be rapidly reversed by metabolic control.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0370-4475
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
135-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
[Effects of strict control of blood sugar by an artificial pancreas on nerve conduction velocity in diabetics].
pubmed:publicationType
Journal Article, English Abstract