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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1982-12-18
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pubmed:abstractText |
In adult rats a saline load is followed by an increase in renal excretion of sodium and by a low rate of ion exchange (hydrogen ions and potassium for sodium), caused by inhibited aldosterone secretion. Under analogous conditions a saline load provoked sodium retention and a distinct increase in renal excretion of hydrogen ions and potassium in young rats, which can be explained by a non-regulated, very intensive ion exchange. The repeated administration of NaCl solution alone and in combination with cyclopenthiazide produced an accelerated maturation of kidney function in 10- and 33-day-old rats measurable by an increase in sodium excretion and reduced ion exchange. In adult rats as well as immediately after birth (5-day-old rats) this effect cannot be provoked by the various pretreatments acting in mature rats.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0047-6374
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
307-13
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7132437-Aging,
pubmed-meshheading:7132437-Animals,
pubmed-meshheading:7132437-Cyclopenthiazide,
pubmed-meshheading:7132437-Female,
pubmed-meshheading:7132437-Hydrogen-Ion Concentration,
pubmed-meshheading:7132437-Ion Exchange,
pubmed-meshheading:7132437-Kidney,
pubmed-meshheading:7132437-Potassium,
pubmed-meshheading:7132437-Rats,
pubmed-meshheading:7132437-Rats, Inbred Strains,
pubmed-meshheading:7132437-Sodium,
pubmed-meshheading:7132437-Sodium Chloride
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pubmed:year |
1982
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pubmed:articleTitle |
Stimulation of renal sodium excretion in mature rats.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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