Linked Life Data

7132352

Source:http://linkedlifedata.com/resource/pubmed/id/7132352

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1982-12-18
pubmed:abstractText
The metabolism of cortisone (E) and cortisol (F) by human placenta, decidua, myometrium, chorion and amnion during pregnancy was studied in vitro. Early pregnancy, midpregnancy and term placentae metabolized F efficiently yielding E as the major product. The capacity of the placenta to inactivate F to E was observed as early as the 8th week of pregnancy and there was a significantly higher (P less than 0.001) net production of E in early pregnancy placenta than in term placenta. In contrast to the placenta, midpregnancy and term decidua metabolized mainly E to F with a net production of F. Term chorion demonstrated an equal degree of oxidative and reductive glucocorticoid metabolism while term amnion and myometrium had negligible metabolic activity. Thus the net production of F from E by the decidual membrane unit is due to metabolic activity in the decidua as early as the 13th week of pregnancy and not to activity in the fetal membranes.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0022-4731
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
371-4
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Glucocorticoid metabolism in human placenta, decidua, myometrium and fetal membranes.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.