Linked Life Data

7128835

Source:http://linkedlifedata.com/resource/pubmed/id/7128835

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1982-12-16
pubmed:abstractText
Electron probe analysis has shown that the high Cl and K contents of smooth muscle reflect the generalized cytoplasmic distribution of these elements and are not due to sequestration in organelles. These findings, in agreement with other studies, indicate that ECl is less and EK more negative than the membrane potential. The susceptibility of cellular Na content to preparatory procedures has been confirmed. Nuclei do not sequester Na, and transmitochondrial monovalent ion (Na, K, Cl) gradients are very small or nonexistent. The major identified intracellular store of Ca is the sarcoplasmic reticulum; mitochondrial Ca is low in resting as well as in maximally contracted normal portal vein smooth muscle. Observations on mitochondrial loading in saponin-skinned smooth muscle suggest that in intact cells maximal contraction may take place at less than 10(-5) M free cytoplasmic Ca2+ concentrations [Ca2+]. Problems of the composition of abnormal (hypertrophied, hypertensive, and atherosclerotic) smooth muscles are considered.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0014-9446
pubmed:author
pubmed:issnType
Print
pubmed:volume
41
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2883-90
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Calcium and monovalent ions in smooth muscle.
pubmed:publicationType
Journal Article, In Vitro, Research Support, U.S. Gov't, P.H.S.