Linked Life Data

7126605

Source:http://linkedlifedata.com/resource/pubmed/id/7126605

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1982-12-18
pubmed:abstractText
In an attempt to elucidate blood group polymorphism systematically in human intestinal tissue, glycosphingolipids of meconia of single individuals have been studied. In this report we describe the major glycosphingolipids in meconium of a newborn typed as a B Le(a-b+) secretor. The glycolipids were analysed as four subfractions obtained after deacetylation of fractions from silicic acid column chromatography of the peracetylated total non-acid glycolipid extract. Chemical characterization (mass spectrometry and 1H-NMR spectroscopy of permethylated and LiA1H4-reduced permethylated derivatives) and immunological characterization (haemagglutination-inhibition of native glycolipids in the liposome form) revealed a very complex pattern of fucosyl-containing glycolipids, probably the result of several blood group glycosyltransferase activities. The major fucolipids, all based on lactotetraosylceramide, had a characteristic ceramide of mainly phytosphingosine and 2-hydroxy fatty acids with 16 and 20-24 carbon atoms.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0006-3002
pubmed:author
pubmed:issnType
Print
pubmed:day
18
pubmed:volume
712
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
274-82
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Chemical fingerprinting of non-acid glycosphingolipids in meconium of a human individual of blood group B Le(a-b+) and secretor.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't