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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
1982-12-21
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pubmed:abstractText |
The effect of blood contamination on the gel-acetylcholinesterase (AChE) test used in the diagnosis of fetal open neural-tube defects was studied with amniotic fluid samples artificially contaminated with fetal or maternal blood in concentrations covering a range exceeding that usually found in clinical practice. Amniotic fluid samples contaminated with maternal blood gave negative gel-AChE results at all concentrations. Contamination with fetal blood yielded positive results if the erythrocyte concentration was greater than about 60 x 10(6) cells/ml. Thus contamination of amniotic fluid with blood is only likely to cause false positive gel-AChE results if this critical concentration is exceeded. Such samples will occur only rarely in clinical practice but when they do the diagnosis should be made with caution.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0306-5456
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
89
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
821-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7126503-Acetylcholinesterase,
pubmed-meshheading:7126503-Amniotic Fluid,
pubmed-meshheading:7126503-Blood,
pubmed-meshheading:7126503-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:7126503-Erythrocyte Count,
pubmed-meshheading:7126503-False Positive Reactions,
pubmed-meshheading:7126503-Female,
pubmed-meshheading:7126503-Fetal Blood,
pubmed-meshheading:7126503-Hematocrit,
pubmed-meshheading:7126503-Humans,
pubmed-meshheading:7126503-Neural Tube Defects,
pubmed-meshheading:7126503-Pregnancy,
pubmed-meshheading:7126503-Prenatal Diagnosis
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pubmed:year |
1982
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pubmed:articleTitle |
False positive gel-acetylcholinesterase results in blood-stained amniotic fluids.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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