Linked Life Data

7118533

Source:http://linkedlifedata.com/resource/pubmed/id/7118533

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1982-12-3
pubmed:abstractText
The 11/2-yr course of idiopathic systemic amyloidosis in a 63-yr-old woman was characterized by inanition, subcutaneous ecchymoses and giant hepatomegaly, the liver weighing 8.5 kg at autopsy. Skeletal survey and bone marrow aspirate were normal. The major components of isolated amyloid fibrils were 16,000- and 23,000-dalton proteins. The 16,000-dalton component was shown by amino acid sequencing to be a fragment of the kappa (k)iv light chain, the first such case. These clinicochemical correlations suggest that isolated massive hepatomegaly may prove to be a hallmark of idiopathic amyloid light chain-related protein k amyloidosis.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0021-2180
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
866-9
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Idiopathic AL-kiv amyloidosis presenting as giant hepatomegaly.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Case Reports, Research Support, Non-U.S. Gov't