Linked Life Data

7114112

Source:http://linkedlifedata.com/resource/pubmed/id/7114112

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1982-10-12
pubmed:abstractText
In the chronic pregnant ewe preparation, daily blood samples, for the determination of plasma cortisol and progesterone levels by specific radioimmunoassay, were obtained from the fetal distal aorta, uterine vein, and uterine artery prior to, during, and after repetitive embolization of the uterine circulation with 15 mu microspheres. A significant increase in fetal cortisol was observed in all animals during the first 3 days of embolization. In those which subsequently entered premature labor, this increase was progressive and was associated with a fall in the uterine venous progesterone level but was unrelated to changes in either the maternal cortisol level or fetal physiologic parameters. In animals which did not enter premature labor, progesterone levels in the uterine vein and estimated progesterone release rates were elevated with an accentuated peak-trough pattern during the postembolization period. In these animals fetal cortisol returned to control levels. The data suggest that cortisol and progesterone biosynthesis within the fetoplacental unit is altered by microembolic placental damage.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0002-9378
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
144
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
47-54
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
The ovine fetoplacental endocrine response to placental damage.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.