Linked Life Data

711223

Source:http://linkedlifedata.com/resource/pubmed/id/711223

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1979-1-15
pubmed:abstractText
Diabetic glomerulosclerosis is a degenerative-proliferative lesion involving most glomeruli in the kidneys of all individuals with hereditary, pancreatic, or experimental diabetes mellitus. The exact nature of the lesion and its etiology remain unknown. Morphologically there appear to be two courses this disease may follow. There is a benign course, which occurred in 89 per cent of our series of adult diabetic patients, consisting of concurrent thickening of the capillary basement membranes and diffuse glomerulosclerosis. The benign course is slowly progressive over many years, and rarely leads to renal failure. The accelerated course, in our experience is always superimposed on the changes of the benign course, and consists of a more rapid progression with the development of glomerulocapillary microaneurysms. Kimmelstiel-Wilson nodules, exudative-deposit lesions, and glomerulocapsular adhesions leading to glomerular obliteration and renal failure. Data are presented to support the concept that large Kimmelstiel-Wilson nodules are formed by the organization of the glomerulocapillary microaneurysms.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0046-8177
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
439-53
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1978
pubmed:articleTitle
A re-evaluation of diabetic glomerulosclerosis 50 years after the discovery of insulin.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.