Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1982-10-29
pubmed:abstractText
To determine whether chronic saline ingestion is required for protection against acute renal failure, we examined the effect of the time at which saline was offered. Water-drinking rats developed severe azotemia (BUN 115 +/- 6 mg/dl; 41 +/- 2 mmol/l) 24 h after 50% glycerol i.m. Chronic saline ingestion for 30 days conferred protection only if continued after the insult (BUN 49 +/- 4 mg/dl; 18 +/- 1 mmol/l; p less than 0.01) but not if saline was withdrawn (BUN 110 +/- 8 mg/dl; 38 +/- 3 mmol/l). Moreover, saline offered only after the insult conferred equivalent protection (BUN 57 +/- 6 mg/dl; 32 +/- 2 mmol/l). Fluid intake, arterial blood pressure and plasma volume were better sustained in saline-drinking rats.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0028-2766
pubmed:author
pubmed:issnType
Print
pubmed:volume
30
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
352-6
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Saline- and glycerol-induced acute renal failure: 'protection' occurs after insult.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.