Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1982-10-21
pubmed:abstractText
Biosynthesis of the peptide egg-laying hormone by the bag cells of Aplysia was monitored throughout the year to determine whether the synthesis of neurosecretory proteins is modulated in accordance with secretory demand. The rate of synthesis of precursors to the hormone was found to vary seasonally, being approximately twofold higher during the late summer egg-laying season than during midwinter. Since there was no change in the distribution of radioactivity among members of the proteolytic processing sequence leading to the hormone, these data imply a seasonal modulation of the production of the secretory product. The synthetic rate showed no correlation with animal maturity or recent egg-laying history. However, there was a significant interaction between the seasonal effect and elevation of hormone synthesis induced by exposure to elevated external potassium, suggesting that these two modulatory factors exert their effects at a common point in the mechanism of hormone biosynthesis.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0022-3034
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
327-35
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Seasonal modulation os synthesis of the neurosecretory egg-laying hormone of Aplysia.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't