Linked Life Data

7108422

Source:http://linkedlifedata.com/resource/pubmed/id/7108422

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1982-10-21
pubmed:abstractText
The fate of mouse blastocyst tissues was examined following reconstitution of blastocysts from isolated inner cell mass (ICM) and trophectoderm differing for electrophoretic variants at the glucose phosphate isomerase (GPI-1) locus. A modified microsurgical method was used and a more sensitive enzyme assay allowed finer dissection of developing chimaeric conceptuses. In seven of nine cases, the extraembryonic ectoderm or the later ectoderm of the chorion was entirely of the blastocyst trophectoderm enzyme type, providing the first direct evidence that this tissue can be wholly derived from the trophectoderm. The two exceptions could represent contamination of the ICM with trophectoderm or might indicate some developmental lability of ICM cells. In addition, the results confirm the cell lineages of other tissues of the 7.5- to 9.5-day pc embryo and, for the first time, directly demonstrate the ICM origin of the parietal endoderm.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0022-0752
pubmed:author
pubmed:issnType
Print
pubmed:volume
68
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
199-209
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Lineage analysis of inner cell mass and trophectoderm using microsurgically reconstituted mouse blastocysts.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't