|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
1
|
|
pubmed:dateCreated |
1982-10-21
|
|
pubmed:abstractText |
An enzyme-linked immunosorbent assay was developed to measure immunoglobulin G (IgG) and IgM type 3 antipneumococcal capsular polysaccharide antibodies. The use of Fab2 fragments of rabbit antipneumococcal IgG antibody in the antibody-antigen sandwich increased the sensitivity for measuring IgM antibodies and decreased background activity in antigen-free cuvettes. This methodology detected type 3 IgM antibody responses in six of six subjects vaccinated with polyvalent pneumococcal vaccine and detected type 3 IgG antibody responses in three subjects. Results of the enzyme-linked immunosorbent assay and radioimmunoassay procedures were concordant, and postvaccination enzyme-linked immunosorbent assay IgM titers showed a stronger correlation with total radioimmunoassay antibody than did postvaccination ELISA IgG titers.
|
|
pubmed:grant |
|
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/7107861-14433,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7107861-204663,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7107861-21849,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7107861-344194,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7107861-344218,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7107861-359992,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7107861-38284,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7107861-4113792,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7107861-43335,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7107861-4607906,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7107861-6154745,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7107861-6986441,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7107861-6988526,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7107861-7007449,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7107861-7380537
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
0095-1137
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
16
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
63-9
|
|
pubmed:dateRevised |
2009-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:7107861-Adult,
pubmed-meshheading:7107861-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:7107861-Female,
pubmed-meshheading:7107861-Humans,
pubmed-meshheading:7107861-Immunoglobulin G,
pubmed-meshheading:7107861-Immunoglobulin M,
pubmed-meshheading:7107861-Male,
pubmed-meshheading:7107861-Polysaccharides, Bacterial,
pubmed-meshheading:7107861-Streptococcus pneumoniae,
pubmed-meshheading:7107861-Vaccines
|
|
pubmed:year |
1982
|
|
pubmed:articleTitle |
Measurement of immunoglobulin G and M antibodies to type 3 pneumococcal capsular polysaccharide by enzyme-linked immunosorbent assay.
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
