Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
129
pubmed:dateCreated
1982-10-29
pubmed:abstractText
Naegleria gruberi amoebae were stimulated to differentiate synchronously into flagellates under growth conditions by lowering the temperature from 32 degrees C to 20.5 degrees C. In the presence of nutrient medium, flagellates will eventually revert to amoebae and resume growth. The time course of nuclear DNA synthesis, using a double thymidine isotope procedure, was determined for: (1) logarithmically growing amoebae, (2) differentiating cells, and (3) flagellates that were reverting to amoebae. DNA replication ceased 10 min. after the stimulation of differentiation, and began again during reversion. Neither de novo transcription nor translation appear to be required for the cessation of DNA replication during differentiation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0011-4529
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
29-38
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
DNA synthesis during growth and synchronous differentiation of Naegleria.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't