Linked Life Data

7104977

Source:http://linkedlifedata.com/resource/pubmed/id/7104977

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1982-10-29
pubmed:abstractText
Isolated cervical lymph node metastases from undifferentiated carcinoma of nasopharyngeal type (UCNT) or lymphoepithelioma (LE) pathologically may be mistaken for malignant lymphomas. The case histories of four patients in whom metastatic UCNT in lymph nodes pathologically simulated Hodgkin's disease (HD) and other non epithelial malignancies are reported. Initial lymph node biopsies showed a cellular and architectural context suggestive of HD in three cases. "Lacunar" cells were seen associated with fibrosis and numerous eosinophils in Case 1; cells indistinguishable from diagnostic Reed-Sternberg cells were recognized in Case 4. Case 3 showed some additional features suggestive of malignant histiocytosis. Subsequent biopsies revealed a primary UCNT of the nasopharynx (Case 1) and typical UCNT lymph node metastases (Cases 3 and 4). In Case 2, an immunoblastic lymphoma and a spindle cell sarcoma, respectively, were mimicked by consecutive lymph node metastases. A primary UCNT of palatine tonsil was found five years later. This report emphasizes that deceptive features of metastatic UCNT in lymph nodes may produce serious difficulties in the correct recognition of the tumor on pure histologic grounds. In order to minimize the possibility of misdiagnosis, additional cytochemical, immunohistochemical and serologic studies should be considered, especially when a young patient presents with spinal or infraclavicular lymphadenopathies and no lesion is evident in the nasopharynx.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0008-543X
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
50
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1344-51
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Pitfalls in microscopic diagnosis of undifferentiated carcinoma of nasopharyngeal type (lymphoepithelioma).
pubmed:publicationType
Journal Article, Comparative Study, Case Reports